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Shiou-Lan Chen Selected Research

Dextromethorphan (Racemethorphan)

2/2020Dextromethorphan Protect the Valproic Acid Induced Downregulation of Neutrophils in Patients with Bipolar Disorder.
2/2017The COMT Val158Met Polymorphism Is Associated With Response to Add-on Dextromethorphan Treatment in Bipolar Disorder.
10/2015ALDH2 polymorphism, associated with attenuating negative symptoms in patients with schizophrenia treated with add-on dextromethorphan.
11/2014Therapeutic effects of add-on low-dose dextromethorphan plus valproic acid in bipolar disorder.
12/2012Dextromethorphan attenuated inflammation and combined opioid use in humans undergoing methadone maintenance treatment.
9/2012Inflammation in patients with schizophrenia: the therapeutic benefits of risperidone plus add-on dextromethorphan.
5/2012The DRD2/ANKK1 gene is associated with response to add-on dextromethorphan treatment in bipolar disorder.

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Shiou-Lan Chen Research Topics

Disease

20Bipolar Disorder (Manic Depressive Psychosis)
02/2020 - 01/2012
13Inflammation (Inflammations)
02/2022 - 06/2012
9Opioid-Related Disorders (Opiate Addiction)
02/2020 - 09/2011
8Alcoholism (Alcohol Abuse)
01/2018 - 06/2009
6Antisocial Personality Disorder (Antisocial Personality)
09/2021 - 06/2009
4Mania (Manias)
01/2018 - 11/2014
3Neurodegenerative Diseases (Neurodegenerative Disease)
02/2022 - 08/2012
3Neuroinflammatory Diseases
01/2021 - 01/2015
3Metabolic Syndrome (Dysmetabolic Syndrome X)
01/2021 - 06/2016
3Heroin Dependence (Heroin Abuse)
10/2017 - 01/2012
3Schizophrenia (Dementia Praecox)
10/2015 - 09/2012
3Anxiety Disorders (Anxiety Disorder)
06/2015 - 01/2013
2Pain (Aches)
01/2022 - 04/2010
2Cognitive Dysfunction
01/2021 - 05/2015
2Substance-Related Disorders (Drug Abuse)
02/2020 - 11/2017
2Necrosis
01/2016 - 01/2016
2Alzheimer Disease (Alzheimer's Disease)
05/2015 - 06/2012
1Hypertension (High Blood Pressure)
10/2022
1Osteoarthritis
01/2022
1Chronic Pain
01/2022
1Apnea
07/2021
1Hypoxia (Hypoxemia)
07/2021
1Encephalitis (Encephalitis, Rasmussen)
01/2021
1Mood Disorders (Mood Disorder)
02/2020
1Delirium
07/2018
1Major Depressive Disorder (Major Depressive Disorders)
10/2014
1Mental Disorders (Mental Disorder)
06/2014
1Bulimia (Binge Eating)
10/2013
1Nerve Degeneration
08/2012
1Depressive Disorder (Melancholia)
07/2010

Drug/Important Bio-Agent (IBA)

16Brain-Derived Neurotrophic Factor (BDNF)IBA
01/2022 - 06/2012
12CytokinesIBA
01/2022 - 09/2012
9Memantine (Namenda)FDA Link
01/2021 - 06/2012
7Dextromethorphan (Racemethorphan)FDA LinkGeneric
02/2020 - 05/2012
7Valproic Acid (Depakote)FDA LinkGeneric
02/2020 - 05/2012
6Aldehyde DehydrogenaseIBA
02/2020 - 01/2012
5Methadone (Dolophine)FDA LinkGeneric
02/2020 - 12/2012
5Dopamine (Intropin)FDA LinkGeneric
06/2015 - 06/2009
4Neuroprotective AgentsIBA
01/2021 - 06/2012
4Nerve Growth Factors (Neurotrophins)IBA
11/2019 - 08/2012
44-aminospiroperidolIBA
11/2017 - 06/2009
3Interleukin-8 (Interleukin 8)IBA
01/2022 - 01/2016
3Transforming Growth Factors (Transforming Growth Factor)IBA
01/2022 - 01/2016
3N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA
07/2021 - 06/2014
3Risperidone (Risperdal Consta)FDA LinkGeneric
01/2016 - 09/2012
3Serotonin ReceptorsIBA
08/2012 - 09/2009
3Serotonin (5 Hydroxytryptamine)IBA
08/2012 - 06/2009
3Morphine (MS Contin)FDA LinkGeneric
06/2012 - 04/2010
2VLDL LipoproteinsIBA
01/2021 - 01/2019
22-methylcyclopentadienyl manganese tricarbonyl (MMT)IBA
11/2019 - 05/2015
2Pharmaceutical PreparationsIBA
01/2016 - 01/2013
2Biomarkers (Surrogate Marker)IBA
01/2016 - 01/2016
2Catechol O-Methyltransferase (Methyltransferase, Catechol)IBA
06/2015 - 03/2015
2Serotonin Plasma Membrane Transport Proteins (Serotonin Transporter)IBA
02/2014 - 07/2012
2Dopamine D2 Receptors (Dopamine D2 Receptor)IBA
02/2014 - 07/2012
2Heroin (Diamorphine)IBA
06/2013 - 12/2012
2Monoamine Oxidase (MAO)IBA
01/2013 - 06/2009
2Opioid Analgesics (Opioids)IBA
12/2012 - 04/2010
2aldehyde dehydrogenase (NAD(P)+) (acetaldehyde dehydrogenase)IBA
09/2012 - 06/2009
21-(2-(dodecyloxy)ethyl)pyrrolidine hydrochloride (DEP)IBA
07/2010 - 09/2009
1Glutamate Receptors (Glutamate Receptor)IBA
10/2022
1Dinoprostone (PGE2)FDA Link
02/2022
1Environmental BiomarkersIBA
01/2022
1Anticonvulsants (Antiepileptic Drugs)IBA
02/2020
1AldehydesIBA
02/2020
1Hemoglobins (Hemoglobin)IBA
02/2020
1Insulin (Novolin)FDA Link
07/2018
1Insulin-Like Growth Factor I (IGF-1)IBA
07/2018
1Interleukin-10 (Interleukin 10)IBA
11/2017
1LipidsIBA
10/2017
1C-Reactive ProteinIBA
10/2017
1Protective AgentsIBA
10/2017
1Triglycerides (Triacylglycerol)IBA
06/2016
1Tumor Biomarkers (Tumor Markers)IBA
01/2016
1InterleukinsIBA
01/2016
1Lorazepam (Ativan)FDA LinkGeneric
01/2016
1Biological ProductsIBA
01/2016
1Fluoxetine (Prozac)FDA LinkGeneric
01/2016
1Alcohol Dehydrogenase (Alcohol Dehydrogenase (NAD+))IBA
08/2015
1Methylenetetrahydrofolate Reductase (NADPH2) (Methylenetetrahydrofolate Reductase)IBA
03/2015
1Glial Cell Line-Derived Neurotrophic Factor (GDNF)IBA
01/2015
1Therapeutic UsesIBA
11/2014
1Venlafaxine Hydrochloride (Effexor)FDA LinkGeneric
10/2014
1Paroxetine (Paxil)FDA LinkGeneric
10/2014
1Milnacipran (Ixel)FDA Link
10/2014
1Dopamine D3 ReceptorsIBA
12/2012
1Neurotransmitter Agents (Neurotransmitter)IBA
09/2012
15-HT2A Serotonin Receptor (5 HT2A Receptor)IBA
08/2012
1Phosphotransferases (Kinase)IBA
07/2012
1Sigma-1 ReceptorIBA
09/2011
1Naloxone (Narcan)FDA LinkGeneric
04/2010
1Analgesics (Analgesic Drugs)IBA
04/2010
1Meperidine (Pethidine)FDA LinkGeneric
04/2010

Therapy/Procedure

5Therapeutics
11/2019 - 08/2012
1Spinal Anesthesia
01/2022
1Ambulatory Care (Outpatient Care)
01/2012